مدرس المادة
The reticular endothelial system is immune complex from blood and tissues, it mainly comprises of phagocytic cells whose engulf microbes, participate in inflammation,antigen presenting and cytokine secretions. The major phagocytic cellsare:
- Polymorphnuclear leucocytes (PMNLs).
- Blood and tissue monocytes.
These phagocytic cells found in many organs as blood, liver, kidney, lung, brain, spleen, and lymph node.
Origin of reticular endothelial cells:
Myeloid progenitor is deriving from hematopoietic stem cells, which can differentiate into myeloid cells.
Myeloid cells are development into two kinds of phagocyte cells:
- Granulocytes cells (PMNs) can be divided into neutrophils, basophils, and eosinophils accordingto cytoplasmic granulesrespond to different dyes.
- Mononuclear cells can be divided into monocytes and macrophages cells.
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