Lecturer
Chronic Inflammation
Prolonged tissue injury causes persistent or chronic inflammation.
Chronic Inflammation may develop:
1. Progressive acute inflammation.
2. Primary chronic inflammation.
Primary chronic inflammation produced by agent
Dust like carbon, silica, asbestosis
Microorganisms like virus, bacteria, fungus, and also large parasite.
Hypersensitivity.
Unknown causes.
Chronic Inflammation
Characteristic features of chronic inflammation are:
1. Infiltration by mononuclear cells “macrophage, lymphocytes
and plasma cells”
2. Proliferation of fibroblasts rather than exudates.
3. The risk of scaring and deformity developing is usually considerably
greater than in acute inflammation.

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