Lecturer
- Serological diagnostic examinations include precipitation reaction, agglutination reaction, complement fixation test, immunofluorescence antibody assay, immunoenzymatic assay, radioimmunoassay, and immunoblotting.
- The serological diagnosis has evolved from serum sedimentation test and agglutination test to immunolabelling technique with efficiency requiring a trace amount of specimen and enzyme linked immunoblotting at the molecular level.
- These immunoassays can be applied to detect circulating antibody or antigen in infected human body, and are expected to be applicable for staging of an infection, identifying active stage of a new infection and assessing the therapeutic efficacy.
- The serological diagnosis is playing an increasingly important role in the clinical diagnosis that the etiological diagnosis fails to. Almost all the immunoassays are applicable for the diagnosis of parasitic diseases but not always effective.
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