Aplastic anemia

Aplastic anemia

• Aplastic anemia is a blood disorder that occurs when the bone marrow produces too few of all types of blood cells: red cells, white cells and platelets (Pancytopenia).

•  A low number of red blood cells reduces the blood’s ability to carry oxygen.

• A reduced number of white blood cells makes the child more susceptible to infection.

• A low number of platelets reduces the blood’s ability to clot.

• Causes of Aplastic anemia:

A. Primary:

1. Idiopathic: occurring with no known reason. The disorder can be the result of a previous illness or presented problem.

2. Inherited genetic disorder.

B. Secondary : (Acquired causes)

1. Specific infectious diseases, such as hepatitis, Epstein-Barr virus, or cytomegalovirus.

2. taking certain medications including some antibiotics and arthritis drugs.

3. Exposure to certain toxins, such as benzene, TNT, Chlordane, and DDT.

4. Exposure to radiation or chemotherapy.